The global Cystic Fibrosis Drug Market size was USD 8.85 billion in 2021, and it is projected to achieve a revenue CAGR of 24.5% during the forecast period. The primary drivers of this growth are the introduction of new therapeutics and technologies for treatment. The demand for bronchodilator drugs is also contributing to the market's revenue growth. Cystic fibrosis impairs the cells that generate mucus, perspiration, and digestive fluids, and about 80% of individuals with this condition are given inhaled bronchodilators to ease symptoms and widen the airways, thereby boosting the market's revenue growth.

Bronchodilators are frequently used to treat chronic conditions in which the airways become constricted and inflamed, such as asthma caused by airway inflammation and Chronic Obstructive Pulmonary Disease (COPD), a lung condition that causes airway blockage. According to the World Health Organization (WHO), roughly 50% of children with cystic fibrosis in developed nations are identified in their first year of life through clinical or family history. Cystic fibrosis is an inherited disease that affects the lungs, pancreas, liver, kidneys, and gut.

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Key players in the Cystic Fibrosis Drug Market –

·         F. Hoffmann-La Roche Ltd

·         Novartis AG

·         Gilead Sciences, Inc.

·         Vertex Pharmaceuticals Incorporated

·         AbbVie Inc.

·         Teva Pharmaceutical Industries Ltd

·         Pharmaxis Ltd

·         Mylan N.V

·         Genentech, Inc.

·         AstraZeneca

This condition causes breathing difficulties and thick, viscous secretions that can be lethal to the lungs, pancreas, liver, and gut, as well as obstructing pancreatic enzymatic functions in the body. For example, research indicates that approximately 40,000 children and adults in the United States are impacted by cystic fibrosis each year.

Segments Covered in the Report –

Cystic fibrosis is a genetic disorder that affects various organs in the body, particularly the lungs and pancreas. The development of cystic fibrosis drugs is an essential area of research, and the global market size for these drugs was estimated at USD 8.85 billion in 2021.

In terms of drug class, the cystic fibrosis drug market can be segmented into several categories, including transmembrane conductance regulator (CFTR) modulators, bronchodilators, mucolytics, pancreatic enzyme supplements, and others. Among these, bronchodilators are expected to drive significant revenue growth due to the high demand for these drugs to alleviate symptoms associated with the narrowing and irritation of airways caused by cystic fibrosis.

The route of administration for cystic fibrosis drugs can be oral or parenteral. While oral administration is preferred by most patients, parenteral administration is necessary for those who cannot tolerate oral medications.

The distribution channels for cystic fibrosis drugs include retail pharmacies and drug stores, online pharmacies, and hospital pharmacies. Retail pharmacies and drug stores are the most common distribution channels, as these locations are easily accessible to patients and their families. Online pharmacies have gained popularity in recent years due to the convenience and accessibility of ordering medications online. Hospital pharmacies are essential for providing cystic fibrosis drugs to patients during hospitalization and for outpatient care.

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In conclusion, the global cystic fibrosis drug market is projected to achieve significant growth in the coming years, driven by advancements in therapeutics and technology. Bronchodilators are a primary driver of this growth due to their high demand among patients with cystic fibrosis. The market for cystic fibrosis drugs can be segmented by drug class, route of administration, and distribution channel, reflecting the diverse needs of patients and their families. Retail pharmacies and drug stores, online pharmacies, and hospital pharmacies all play critical roles in providing access to cystic fibrosis drugs to those in need.

Strategic development:

A strategic research cooperation and licensing agreement was announced on September 16, 2020, between Moderna, Inc. and Vertex Pharmaceuticals Incorporated. The partnership aims to develop lipid nanoparticles (LNP) and mRNAs to deliver gene-editing treatments for cystic fibrosis (CF) treatment. The focus of the three-year research cooperation is the discovery and optimization of novel LNPs and mRNAs capable of delivering gene-editing therapies to lung cells. This would enable the production of functional cystic fibrosis transmembrane conductance regulator (CFTR) protein, which is essential for the treatment of CF.

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